What do the "call" and "risk allele" columns on my StrateGene report mean?Updated 4 months ago

The "call" column on the tables section of your StrateGene report lists the alleles you inherited from each parent (mother and father) on that particular gene.

The "risk allele" is the allele that contains a mutation on the gene that has been show in research to have an effect on health, or have health implications. If you inherited this risk allele, it will match one of the letters in the "call" section from your parents.

If you inherited a mutation from only one parent, then your findings will report "heterozygous" or "+/-" in yellow. If you inherited that mutation from both parents, your StrateGene will report "homozygous" or "+/+" in red.  You will see that if there is no mutation present (wild type), the "call" column that you inherited from your parents does not match the "risk allele".

Keep in mind that significance of risk alleles depends on the SNP and your lifestyle (epigenetics).  This is why reading Dirty Genes and learning about epigenetics in further detail with the Dirty Genes Course and SHEICON series is really important.

As a reminder, the "call" column and the "risk allele" does not have anything to do with immediate bonding of complementary nucleotides, only what is inherited. Your immediate bonding of nucleotides will have A-T or C-G bonds (complementary).