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Dr. Lynch product Q&AUpdated 7 hours ago

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I took this and had stomach pain through the night and into the next morning. Is that normal? I only took it once so I'm not sure if I should keep trying it or is it not for me?

This is called 'remodeling' and is a common experience for those who have a microbiome that needs support.

The stomach pain is likely caused by the beneficial probiotics competing with the bad microbiome in your gut.

As the bad bugs die, they release a lot of gas. The gas is likely causing distention and pain.

I recommend adding Gallbladder Nutrients - 1 to 2 capsules before dinner. This supports healthy bile production and bile flow. This is needed also to support a healthy microbiome. It also helps healthy bowel movements.
https://www.seekinghealth.com/products/gallbladder-nutrients

Then take the ProBiota HistaminX after dinner.

After a week, the bloating should be significantly less.

You may also benefit from Saccharomyces Boulardii. I would add take 1 capsule of this beneficial yeast after dinner with the ProBiota HistaminX. This also competes with the non-friendly bacteria and yeasts but in a different way so it's more comprehensive.
https://www.seekinghealth.com/products/saccharomyces-boulardii

In health,


I see you include Ascorbyl Palmitate in the ingredients in the glutathione lozenge. I have been learning that it's common in the supplement industry to put the ascorbyl palmitate thru a fermentation process. Does your ascorbyl palmitate go thru a fermentation process? Does Probiota HistaminX go through a fermentation process?

Many vitamins go through a fermentation process as it is a healthy way to create nutrients.

I am not sure if ascorbyl palmitate of ours goes through this process or not.

That said, even if it does, the benefits of ProBiota HistaminX and any of our histamine support supplements far outweigh the potential of fermentation issues.

We are likely the best in the world when it comes to histamine support. Our formulations are extremely effective.

In the event they do not perform for you, simply ask for a refund.

In health,


Does probiota histaminX contains quercetin? As I buying this product in Australia. Its been stocked here by 5th element, I saw under the ingredients list it contains quercetin, so just curious to know. Thank you.

There is no quercetin in ProBiota HistaminX. This supplement is a probiotic which contains healthy strains of bacteria.

There is quercetin in HistaminX. HistaminX supports healthy histamine storage within the cells.

Perhaps that is the confusion.

In health,


I love your products but why did you decide to include L.Plantarum. It's know for producing high D-lactate which can produce digestive and neurological problems especially with people with Short Bowel Syndrome and autism. People who try to avoid histamine too. Would you be willing to remove this in your next batch?

The lactate produced from the microbiome is not significant as what our own body makes.

I've discussed this exact theory with probiotic experts in the field.

Lactate is elevated in those with mitochondrial dysfunction.

Supporting healthy mitochondria is what's needed for those struggling with autism or other types of neurological dysfunctions.

L. plantarum is incredibly supportive of healthy histamine levels.

In health,


Good afternoon. I started taking this product because of chronic loose stool issues/diarrhea. After a couple of doses it turned completely around to constipation issues. I then reduced to 1 capsule every other day. Still having constipation issues on day one and maybe day 2 and maybe not on day 2. So looking for advice as I have had issues for about 30 years and just been diagnosed with HaT Hereditary Alpha Tryptasemia. Tryptase always in the upper teens. I am also looking for any other recommendations for high long term 20 years of stress. I don't know if I am methylating properly or not. I did take B12 for a time a long time ago and my labs came back high so I quit. I don't know if I need B vitamins or not. I just need help in settling down my heart rate, brain fog, bathroom issues, histamine, mast cells. Thank you in advance. I am grateful for what you do Dr. Lynch and I've heard many good things about your company through our online support group and I was inspired by your video. I want to use your products but I need some guidance on where to start. TY

Thank you for your comments.

It's common to have what they call 'gut remodeling' when starting a new probiotic.

I'd continue using ProBiota HistaminX and only using it a few nights a week - taken after dinner.

B12 high on labs is common when one is supplementing. If you feel good taking vitamin B12, continue taking it.

I'd consider Gallbladder Nutrients - 2 capsules before dinner. Start there. If needing more support, consider 2 capsules before lunch and 2 before dinner. You want stools to be well formed, easy to pass and sink. Find the amount that works for you - it may be, and usually is, more in the beginning stages for the first week and then less as you improve.

Upon waking, I'd do two things:

Optimal Electrolyte Unflavored: sip 1 serving in a glass of filtered water

Glutathione Plus Lozenge: take 1/2 lozenge, let it dissolve and then swallow.

These should help significantly ;)

In health,


Hi, I purchased this product in hopes of helping with hot flashes. At first I thought hot flashes d/t hormones (d/t my age) but then I started noticing if I ate certain food, I would have immediate hot flashes and my hands get red and hot, so now I am thinking it is a histamine response. I tried Probiota HistaminX for 2 days. It made my hot flashes, hands worse and constipation worse. Do you have any suggestions on where to go from here? Thank you

I would use Histamine Digest and Gallbladder Nutrients.

Take Histamine Digest with meals.

Take Gallbladder Nutrients, 2 capsules, before dinner. If you experience a healthy bowel movement that's easy to pass, sinks and is well formed, then stay with 2 capsules before dinner. If you notice you need more support, add either 2 capsules before lunch and 2 before dinner - or take 4 capsules before dinner.

The ProBiota HistaminX may be added about 1 month after trying the above.

You may need more gallbladder, liver and gut support before using the ProBiota HistaminX.

In health,


Hi! Love your products!! How come it comes in an acid resistant capsule if you are able to open it and empty contents into food or water? Thanks!

Probiotics naturally are found on the food we eat and drinks we drink.

This is why it's possible to open the probiotic capsule and dump the contents onto a bite of food. Then be sure you take it at the END of a meal vs the beginning - to increase the survival rate.

That said, some of the bacteria will die when one opens the capsule.

We use acid-resistant capsules to ensure survivability through the stomach for optimal delivery of the probiotics.

We also use a very special, and expensive, container to keep the probiotics stable.

This is why we don't have to ship any of our probiotics with ice. Our containers are top notch and have been through stability testing ensuring that our probiotics maintain label claim even if sitting in a very hot delivery truck or porch.

It is best to swallow the capsule but if not possible, then it's better to get some of the probiotic than none.

Again, if needing to open the capsule, do it near the end of your meal and place on a bite of food. It's best this way vs mixing in a drink as the probiotic will stick to the side of the glass.

In health,


Is ProBiota HistaminX suitable for a child of 12 years old? Thank you!

Yes. ProBiota HistaminX is suitable for ages 4 and up ;)

Best to give after dinner.

In health,


Probiota Histaminix exipiry date from the production date on the box?

The ProBiota HistaminX is stamped with an EXP date, product testing supports a 2-year shelf life, the EXP printed on the bottle will be for 2 years from time of manufacture.

In Health,


What is the difference between ProBiota Woman and ProBiota HistaminX I am not sure which one to pick and I can only get 1 of them. I am 70 disabled post menopausal with IBS, Interstitial cystitis, Arthritis, FM, have some yeast issues.. etc. I cannot afford to get constipated, please help. Thank you. The HistaminX has many more reviews and I cannot figure out why. Thank you.

ProBiota Woman supports a healthy vaginal flora.

ProBiota HistaminX supports healthy histamine levels - primarily in the digestive system.

I recommend you consider ProBiota HistaminX.

Take 1 capsule after dinner.

I highly recommend also going 100% gluten-free and dairy-free for 14 days. See how you feel at the end of 14 days.

100% avoidance - not even a bite. Just one bite could trigger your immune system and reset all progress.

If you feel significantly better, then I would continue being gluten-free and dairy-free.

Dairy and wheat/gluten is not what they used to be 20 years ago. They are really causing issues in many people.

I am 100% gluten-free and cow dairy-free. I eat goat dairy products without any issue.

In health,


I see you discontinued the powder version. That had 25 billion. Are we to assume this product is equal potency? Even though it only has 10 billion. Also, why is it recommended to take at night?

The formulation is the same between the former powder and the capsules.

The potency is the only difference.

When I was testing my original ProBiota HistaminX formulation of 20 billion per capsule during pilot tests, I found that 20 billion was causing constipation in people after 1 week of use.

That is why I reduced the potency from 20 billion to 10 billion in the capsules. Then I doubled the servings from 30 to 60.

I recommend taking at night after dinner. It gives the probiotic time to make a home in your colon vs being pushed out by other meals consumed throughout the day.

Bacteria naturally are ingested and make their way through our digestive tract.

By taking it at night, you're increasing their ability to take residence.

Plus, some people have what's called 'remodeling' of their gut bacteria. This stage can be uncomfortable with gas and bloating. By taking it at night, gas and bloating can occur while you're sleeping vs during the day.

In health,


Do these help with hives?

Hives are associated with high histamine.

Histamine is often times absorbed through the digestive tract, getting into the blood and then affecting the skin and brain.

ProBiota HistaminX supports healthy histamine levels in the digestive system. It does this by providing bacteria which are known to break down histamine and not produce histamine. I recommend taking this in the evening before bed.

Histamine Digest also supports healthy digestive levels in the digestive system. It does this by providing the DAO enzyme which directly breaks down histamine. I recommend using Histamine Digest with meals.

For a more comprehensive full-body healthy histamine support, consider Histamine Nutrients. Take 2 capsules any time of day as needed. If one wants to support healthy onset of sleep, taking 2 before bed is a good time to do it.

In health,
Dr. Lynch


I read somewhere that L. Plantorum produces Hydrogen Peroxide. Is this the case with this supplement?

L. planetarium actually does the opposite.

"To overcome the deleterious effects of hydrogen peroxide, Lactobacillus plantarum elicits an adaptive response to oxidative stress." PMID 31948630

"Antioxidant activity is one of the important probiotic characteristics for lactic acid bacteria including Lactobacillus plantarum, which is used for food fermentation or as a probiotic supplement." PMID 32865760

In health,
Dr. Lynch


Are they supposed to come in a cold pack when I order from Amazon?
Thank you for your question! Probiotics are not shipped with an ice pack as they have been tested to withstand high temperatures of 104 degrees without losing potency. For more information about probiotics in relation to extreme temperatures, please check out our learning center article here: https://support.seekinghealth.com/hc/en-us/articles/115009433627-Can-my-probiotic-be-exposed-to-very-hot-or-cold-temperatures-
why is there such a low number of bacteria in the product?
Thank you for your question! Higher bacteria counts don't always equal a better Probiotic. Typically, Probiotics with really high CFU's are meant to be used therapeutically, not long term. For instance, if you are taking antibiotics, you would want a stronger probiotic to replenish the good bacteria in the gut. Probiota HistaminX is a great daily probiotic for individuals looking for a healthy histamine response in the gut.
Is it bacteria based or yeast based?
Both. However, the fermentation media used to grow the strains is fully removed as the strains move through the manufacturing process post-fermentation. The result is that there is no residual ingredients present from the fermentation media once the probiotics reach their final ingredient stage.
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