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StrateGene Genetic Analysis Tool (V1)

StrateGene Genetic Analysis Tool for Report Version 1 using Ancestry and 23andMe Data

How important is genetic testing for my health?

According to Dr Lynch, genetic testing, such as 23 and Me and StrateGene, is not necessarily needed, until the basics of health are addressed -the fundamentals. To start out on addressing these fundamentals, read Dr Lynch's book Dirty Genes, and foll

What do the "call" and "risk allele" columns on my StrateGene report mean?

The "call" column on the tables section of your StrateGene report lists the alleles you inherited from each parent (mother and father) on that particular gene. The "risk allele" is the allele that contains a mutation on the gene that has been show in

Why does Ancestry no longer report on my APOE genotype?

AncestryDNA has pulled this SNP from their reporting. There is some speculation with how AncestryDNA reported on APOE SNP RS# 429358 as stated here: https://www.snpedia.com/index.php/Gs246. If you would like to get your reporting on this genotype, 23

I am not finding by gene in the raw data, but the gene is showing up in my report. Can you explain?

There are many different RSID’s for genes. Depending on which RSID you are looking at will determine if there is a deletion or not. You cannot look at the gene itself – make sure to link both gene and RSID when searching in the raw data in order to u

I'd purchased the report and the version number I have is 1.18, what is the current version?

StrateGene is currently undergoing a major update. We are currently working on releasing a new StrateGene version, stay tuned by joining the StrateGene Facebook Group and subscribe to our email list.

I just did 23 and Me and noticed that when I search the raw data, one of the SNPs that StrateGene is supposed to report on is missing. Why is the happening and should I still purchase StrateGene?

It may not show up in your raw data because 23andMe could not confidently report it based on your sample. The quality of your DNA at the specific location may have been inferior, such as due to a poor sample or other issue with the gene itself. This

Does StrateGene report report on APOE 2 and 4?

Yes, StrateGene reports on APOE, 2, 3 and 4. Learn more here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726719/

On my StrateGene report, why are some SNPs reported as "red" (homozygous) for the wild type allele, not the minor variant?

Please note that if you are homozygous for the wild type allele, then it would be reported as "green", or -/-. If you are homozygous for the risk allele, then it would be reported as "red", or +/+. Wild type is not always the major allele nor is the

Where do I start with understanding my StrateGene report?

We offer a number of resources to help you prepare for reading and understanding your StrateGene Report.

What are some resources to supply my doctor with to help them understand the report better? (Aside from the bibliography)

The best course for understanding StrateGene and Pathway Planner Application is SHEICON 2017, available on DrBenLynch.com. This conference goes into specifics and provides patient case studies. Link to purchase: SHEICON 2017

Will StrateGene ever offer me supplement suggestions?

StrateGene offers information about susceptibilities and how to support them. If one has a genetic susceptibility, then StrateGene will point it out. StrateGene does inform the reader which nutrients can support the particular gene but it does not

What is meant by orientation or ambigous flip?

Simply put, the DNA double helix strand can be read in two directions commonly referred to as forward (plus)/top or reverse (minus)/bottom orientation. In terms of the nucleotides for that SNP, the pairing of A with T, and C with G, in the DNA double

What is the story about VDR mutations and how they affect an individual?

VDR (Vitamin D Receptor) does not code for an enzyme, but rather a nuclear transcription regulating factor which triggers proteins involved in bone mineral homeostasis and is a crucial mediator of Vitamin D on cell regulation and metabolism. The infl

What is cell danger response (CDR)?

CDR is a concept developed by Robert K. Naviaux, MD, PhD, and he puts it this way:. "Cells have a limited number of ways they can respond to threats. An important consequence of this is that evolutionary selection preserves similar cellular responses